DCS PHARMA

Useful References

Validation

  • EU GMP Annex 15 – Qualification and Validation
  • EU GMP Annex 11 – Computer Systems
  • ASTM E2500
  • ISPE
  • GAMP 5
  • FDA 21CFR Parts 210 , 211
  • FDA 21CFR Part 11 – Electronic Records and Signatures
  • EU GMP Annex 1 : Manufacture of Sterile Medicinal Products

Pharmaceutical Development and Commercialisation

  • EudraLex Volume 4, GMP Part II – Basic Requirements for Active Substances used as Starting Materials
  • FDA Guidance for industry: Drug Substance Chemistry, Manufacturing, and Controls Information (Contains Non-Binding Recommendations)
  • ICH Q7 -GMP for Active Pharmaceutical Ingredients
  • ICH Q8 – Pharmaceutical Development
  • ICH Q9 – Quality Risk Management
  • ICH Q11 Development and Manufacture of Drug Substances
  • ICH Q1 A (R2) Stability Testing of new Drug Substances and Products
  • ICH Q3A : Specification for degradation Products
  • ICH Q6A , Q6B : Specification, which is a list of tests, reference to analytical procedures, and proposed acceptance criteria
  • WHO Annex 1 – Guidelines for assuring quality and non-clinical safety evaluation of DNA Vaccines

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